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NF-κB Reporter (Luc) - NIH/3T3

Cell line
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  • BPS Bioscience已认证
  • 79469
  • 美国
  • 2025年12月20日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      1

    • 供应商

      BPS Bioscience

    • 细胞类型

      稳转细胞系

    • 品系

      NIH/3T3

    • 组织来源

      /

    • 相关疾病

      多种

    • 物种来源

      mouse

    • 免疫类型

      多种

    • 器官来源

    • 运输方式

      干冰

    • 年限

      10

    • 生长状态

      良好

    • 英文名

      NF-κB Reporter (Luc) - NIH/3T3 Cell line

    • 规格

      2管

    The NF-κB reporter (Luc)-NIH/3T3 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

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    图标文献和实验
    该产品被引用文献
    • Monitor NF-κB signaling pathway activity. • Screen for activators or inhibitors of NF-κB signaling pathway.
    相关实验
    • 细胞信号通路相关文献

      . In this study, we characterized the pharmacological profile of a novel curcumin analog P1 and elucidate the related mechanisms.Methods:HEK293/NF-κB cells, stably transfected with an NF-κB-responsive luciferase reporter plasmid, were generated for high-throughput

    • Microscopic Imagery of Mammalian Cells Expressing an Enhanced Green Fluorescent Protein Gone

      The green fluorescent protein (GFP; 1 –5 ) from the jellyfish Aequorea Victoria has emerged as an important reporter for monitoring gene expresston, protein localization, cell transformation, and cell lineage in VIVO and in real time

    • LINEAGE ANALYSIS USING RETROVIRAL VECTORS

      to define the cell types expressing the reporter gene. In some cases, the morphology of the infected cells indicates their identity. In such cases, we recommend that one use lacZ or PLAP with histochemical detection, which is the simplest and most rapid way

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    NF-κB Reporter (Luc) - NIH/3T3 Cell line
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