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- 库存：
99
- 英文名：
PE anti-human β2-microglobulin
- 供应商：
北京云肽生物科技有限公司
BioLegend 395704 PE anti-human β2-microglobulin
北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 395704 PE anti-human β2-microglobulin
产品简介：
产品品牌：BioLegend
产品货号：395704
产品名称：BioLegend 395704 PE anti-human β2-microglobulin
产品规格：100 tests
产品说明：
Clone A17082A (See other available formats)
Regulatory Status RUO
Other Names
β2M, β2-M, beta2-microglobulin b2-M, b2M
Isotype Mouse IgG1, κ
描述
β2-微球蛋白（β2M）是一种12 kD非多态性Ig样蛋白。它是一种非膜锚定糖蛋白，与MHC I类分子的39-44 kD多态性重链非共价结合，形成HLA I类抗原复合物。与 HLA I 级相关，β2M 在所有白细胞、血小板、内皮细胞和上皮细胞上表达。β2M在控制MHC I类分子稳定性和促进抗原结合和将抗原呈递给CD8+ T细胞的CD3 / TCR复合物方面起着至关重要的作用。
β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.
Product Details
Isotype Control PE Mouse IgG1, κ Isotype Ctrl (FC)
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen Recombinant human Beta2-microglobulin
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Antigen Details
Structure 12 KD, Ig like structure
Distribution
Leukocytes, platelets, endothelial cells, epithelial cells and other nucleated cells.
Function Form MHC class I
Interaction
MHC class I heavy chain and other MHC I like molecules.
Cell Type
Antigen-presenting cells, Endothelial cells, Epithelial cells, Leukocytes, Platelets
Biology Area
Cancer Biomarkers, Immunology, Innate Immunity
Molecular Family MHC Antigens
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文献和实验相关实验
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BioLegend 395704 PE anti-human β2-microglobulin
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