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- 库存：
99
- 英文名：
PE anti-human CD80 Recombinant
- 供应商：
北京云肽生物科技有限公司
BioLegend 370612 PE anti-human CD80 Recombinant
北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 370612 PE anti-human CD80 Recombinant
产品简介：
产品品牌：BioLegend
产品货号：370612
产品名称：BioLegend 370612 PE anti-human CD80 Recombinant
产品规格：100 tests
产品说明：
Clone QA18A16 (See other available formats)
Regulatory Status RUO
Other Names B7-1, B7, BB1
Isotype Mouse IgG1, κ
描述
CD80，也称为B7-1，B7和BB1，是一种60 kD单链I型糖蛋白，属于免疫球蛋白超家族。CD80 在活化的 B 和 T 细胞、巨噬细胞和树突状细胞上表达。CD80与CD28和CD152（CTLA-4）结合。与CD86一起，CD80在T细胞活化的调节中起着关键作用。CD80与CD28的相互作用为通过CD3复合物激活T细胞提供了有效的共刺激信号，而其与CTLA-4的相互作用为T细胞活化提供了抑制信号。
CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
Product Details
Isotype Control PE Mouse IgG1, κ Isotype Ctrl (FC)
Verified Reactivity Human
Antibody Type Recombinant
Host Species Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Antigen Details
Structure
Ig superfamily, single chain type I transmembrane glycoprotein, 60 kD
Function T cell costimulation
Ligand/Receptor CD28, CD152 (CTLA-4)
Cell Type B cells, Dendritic cells, Macrophages, T cells, Tregs
Biology Area
Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules, Immune Checkpoint Receptors
以下是 BioLegend 品牌部分产品，如需其他产品请联系本公司销售。
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BioLegend 310904 FITC anti-human CD69 FN50 100 tests
BioLegend 310908 PE/Cyanine5 anti-human CD69 FN50 100 tests
BioLegend 310909 APC anti-human CD69 FN50 25 tests
BioLegend 310910 APC anti-human CD69 FN50 100 tests
BioLegend 310911 PE/Cyanine7 anti-human CD69 FN50 25 tests
BioLegend 310912 PE/Cyanine7 anti-human CD69 FN50 100 tests
BioLegend 310914 APC/Cyanine7 anti-human CD69 FN50 100 tests
BioLegend 310918 Alexa Fluor® 647 anti-human CD69 FN50 100 tests
BioLegend 310919 Pacific Blue™ anti-human CD69 FN50 25 ug
BioLegend 310922 Alexa Fluor® 700 anti-human CD69 FN50 100 ug
BioLegend 310925 PerCP/Cyanine5.5 anti-human CD69 FN50 25 tests
BioLegend 310926 PerCP/Cyanine5.5 anti-human CD69 FN50 100 tests
BioLegend 310927 PerCP anti-human CD69 FN50 25 tests
BioLegend 310928 PerCP anti-human CD69 FN50 100 tests
BioLegend 310929 Brilliant Violet 421™ anti-human CD69 FN50 25 tests
BioLegend 310930 Brilliant Violet 421™ anti-human CD69 FN50 100 tests
BioLegend 310935 Brilliant Violet 510™ anti-human CD69 FN50 25 tests
BioLegend 310936 Brilliant Violet 510™ anti-human CD69 FN50 100 tests
BioLegend 310937 Brilliant Violet 605™ anti-human CD69 FN50 25 tests
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文献和实验相关实验
Non-Replicating Recombinant Vaccinia Virus Expressing CD80 to Enhance T-Cell Stimulation
The following method describes the generation of a recombinant vaccinia virus expressing a costimulatory molecule (human CD80 or B7.1). The procedure first requires the cloning, by classical methods not described here, of the gene
度的功能细胞。二、人外周血中 CD4 T 细胞分选实例1.产品信息： MojoSort™ Human CD4 T Cell Isolation Kit（BioLegend, Cat#480009），阴性分选试剂盒2.检测仪器型号：BD LSRⅡ3.样本：正常人外周血4.分选前后检测相关产品：PE-CD4（Biolegend, Cat# 317410）5.实验过程（1）采血之后采用达优™ 人淋巴细胞分离液分离人外周血单个核细胞。分离之后能见到明显的白膜层。（达优，Cat#DKW-KLSH-0100
Live‐Cell Immunofluorescence Staining of Human Pluripotent Stem Cells
Stains live MEFs; PE bleaches rapidly hCD13 Biolegend
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BioLegend 370612 PE anti-human CD80 Recombinant
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