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- 详细信息
- 文献和实验
- 技术资料
- 库存：
99
- 英文名：
Alexa Fluor® 488 anti-human CD56 (NCAM)
- 供应商：
北京云肽生物科技有限公司
BioLegend 318312 Alexa Fluor® 488 anti-human CD56 (NCAM)
北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 318312 Alexa Fluor® 488 anti-human CD56 (NCAM)
产品简介：
产品品牌：BioLegend
产品货号：318312
产品名称：BioLegend 318312 Alexa Fluor® 488 anti-human CD56 (NCAM)
产品规格：100 tests
产品说明：
Clone HCD56 (See other available formats)
Regulatory Status RUO
Other Names Leu-19, NKH1
Isotype Mouse IgG1, κ
描述
CD56是一种单一的跨膜糖蛋白，也称为NCAM（神经细胞粘附分子），Leu-19或NKH1。它是Ig超家族的成员。140 kD亚型在NK细胞和NK-T细胞上表达。CD56也在大脑（小脑和皮层）和神经肌肉接头中表达。某些大颗粒淋巴细胞 （LGL） 白血病、小细胞肺癌、神经元源性肿瘤、骨髓瘤和骨髓性白血病也表达 CD56。CD56通过与自身或硫酸肝素结合在同性和异性粘附中发挥作用。
CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.
Product Details
Isotype Control
Alexa Fluor® 488 Mouse IgG1, κ Isotype Ctrl (FC)
Verified Reactivity Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type Monoclonal
Host Species Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses
Excitation Laser Blue Laser (488 nm)
Application Notes
Clone HCD56 is not recommended for immunohistochemistry formalin-fixed paraffin-embedded tissue.
Antigen Details
Structure
Ig superfamily, single transmembrane or GPI-anchored glycoprotein
Distribution
NK cells, T subset, neural tissue, some LGL and myeloid leukemias
Function Adhesion
Ligand/Receptor Heparin sulfate
Cell Type
B cells, Leukemia, Mesenchymal Stem Cells, Neurons, NK cells, T cells
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family Adhesion Molecules, CD Molecules
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BioLegend 318312 Alexa Fluor® 488 anti-human CD56 (NCAM)
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