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- 详细信息
- 文献和实验
- 技术资料
- 库存:
99
- 英文名:
PE anti-mouse CD196 (CCR6)
- 供应商:
北京云肽生物科技有限公司
北京云肽生物科技有限公司作为BioLegend的特约经销商,为广大客户提供原装正品,货期短,折扣好的服务准则。
美国BioLegend公司位于美国加州,致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长,但它聚集了一批来自PharMingen公司的专业人士,建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势,以及与世界知名实验室和研究所的良好合作关系,以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证,提供各种质量卓越的产品,并不断地开发新产品,以满足飞速发展的生命科学研究的需要。
BioLegend 129804 PE anti-mouse CD196 (CCR6)
产品简介:
产品品牌:BioLegend
产品货号:129804
产品名称:BioLegend 129804 PE anti-mouse CD196 (CCR6)
产品规格:100 µg
产品说明:
Clone 29-2L17 (See other available formats)
Regulatory Status RUO
Other Names CD196, BN-1, CKR-L3, DRY6, KY411, STRL22
Isotype Armenian Hamster IgG
描述
CCR6是一种G蛋白连接的趋化因子受体,其结合趋化因子CCL20/MIP-3a。它在B淋巴细胞和某些树突状细胞和T细胞亚群上表达。据报道,CCR6参与粘膜免疫反应、淋巴细胞迁移和稳态。
CCR6 is a G-protein linked chemokine receptor which binds the chemokine CCL20/MIP-3a. It is expressed on B lymphocytes and certain subsets of dendritic cells and T cells. CCR6 is reported to be involved in mucosal immune response and lymphocyte migration and homeostasis.
Product Details
Isotype Control PE Armenian Hamster IgG Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Armenian Hamster
Immunogen N-terminal peptide (aa. 2-38) of mouse CCR6 fused with GST
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Antigen Details
Structure
G-protein linked, seven transmembrane, domain-spanning chemokine receptor; 367 amino acids long and about 75% homology with human CCR6
Distribution
Expressed on spleen B cells, immature splenic dendritic cells in Peyer's patches, and some T cell subset
Function Important in regulating mucosal immune response
Ligand/Receptor CCL20/MIP-3a
Cell Type B cells, Dendritic cells, T cells
Biology Area Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
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T-cell dependent antigen specific in situ staining (Pe)
6- Wash twice in TBS-T. 7- counterstain with rabbit anti B-Pe 1:2000 (0.5 µg/ml Cortex Biochem). You may add 1% mouse serum to the anti-Pe antibodies, unless you plan to use mouse monoclonal further (see below). 8- wash twice in TBS-T. 9- block
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