产品说明: Clone KH95 (See other available formats) Regulatory Status RUO Other Names MHC class I Isotype Mouse (BALB/c) IgG2b, κ
描述 KH95抗体与在来自H-2Db单倍型小鼠的有核细胞上表达的H-2Db-MHC I类同种抗原反应。H-2Db参与向表达CD3/TCR和CD8蛋白的T细胞的抗原呈递。与其他单倍型(如a、d、f、k、n、p、q、r、s、u、v)的反应性尚未报道。 The KH95 antibody reacts with the H-2Db MHC class I alloantigen expressed on nucleated cells from mice of the H-2Db haplotype. H-2Db is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins. Reactivity with other haplotypes (e.g., a,d,f,k,n,p,q,r,s,u,v) has not been reported.
Product Details Isotype Control FITC Mouse IgG2b, κ Isotype Ctrl Verified Reactivity Mouse Antibody Type Monoclonal Host Species Mouse Immunogen C57BL/10 mouse skin graft and splenocytes Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. Concentration 0.5 mg/ml Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. Application FC - Quality tested Recommended Usage Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application. Excitation Laser Blue Laser (488 nm) Application Notes Additional reported applications (for the relevant formats) include: complement-dependent cytotoxicity1, and Western blotting.
Antigen Details Structure MHC class I Distribution Nucleated cells of the H-2Db haplotype Function Antigen presentation Ligand/Receptor CD3/TCR, CD8 Biology Area Immunology, Innate Immunity Molecular Family MHC Antigens
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