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- 2025年12月05日
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2941376-76-5
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RXFP1 receptor agonist-4
CAS No. : 2941376-76-5
MCE 国际站：RXFP1 receptor agonist-4
产品活性：RXFP1 receptor agonist-4 (Example 268) 是一种 RXFP1 受体 激动剂。RXFP1 receptor agonist-4 抑制稳定表达人 RXFP1 的 HEK293 细胞中 cAMP 的产生，EC50 值为 4.9 nM。
研究领域：Others
作用靶点：Others
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文献和实验Autoradiographic Visualization in Brain of Receptor-G Protein Coupling Using [35S]GTPS Binding
-stimulated [35 S]guanylyl-5′-O-(γ-thio)-triphosphate ([35 S]GTPγS) binding, originally developed for receptors in isolated membranes, has provided an excellent opportunity to apply this process to brain sections, thus allowing the visualization of receptor
the mechanism of agonist efficacy: A relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor. Mol. Pharmacol. 76:543‐551. Summerhill, S., Stroud, T
Methods for Evaluation of Positive Allosteric Modulators of Glutamate AMPA Receptors
in the presence of bound agonist. Despite this commonality, positive allosteric modulators can be segregated on the basis of the preferential effects on AMPA receptor subunits, their alternatively spliced variants and/or their biophysical mechanism of action
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