PTP1B/AKR1B1-IN-2

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PTP1B/AKR1B1-IN-2

CAS No. :

MCE 国际站：PTP1B/AKR1B1-IN-2

产品活性：PTP1B/AKR1B1-IN-2 (Compound 7f) is a dual PTP1B/AKR1B1 inhibitor (IC₅₀s: 3.2 and 2.1 μM, K_is: 4.0 and 0.9μM). PTP1B/AKR1B1-IN-2 is an insulin-mimetic agent. PTP1B/AKR1B1-IN-2 improves glucose uptake in murine C2C12 myoblasts. PTP1B/AKR1B1-IN-2 can be used for research of Type 2 diabetes mellitus (T2DM).

研究领域：Metabolic Enzyme/Protease

作用靶点：Phosphatase  |  Aldose Reductase

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