IL2/IL2蛋白Recombinant Human Int

纯度：

Greater than 95% as determined by SDS-PAGE.

基因名：

IL2

Uniprot No.：

P60568

别名：

IL-2;T-cell growth factor (TCGF);Aldesleukin

种属：

Homo sapiens (Human)

蛋白长度：

Full Length of Mature Protein

来源：

Mammalian cell

分子量：

41.5 kDa

表达区域：

21-153aa

氨基酸序列：

APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT

蛋白标签：

N-terminal hFc-tagged

产品提供形式：

Lyophilized powder

缓冲液：

PBS, pH 7.4, 6% trehalose

货期：

3-7 business days

注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

功能：

Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R.

内毒素：

Less than 1.0 EU/ug as determined by LAL method.

SDS-PAGE:

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS Image Description/Western Blot:

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Product types:

Active Protein & In Stock Protein

Biological_Activity:

Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA(CSB-MP011649HU3) at 2 μg/mL can bind Human IL2 , the EC50 is 0.4992 to 0.6269 ng/mL.

Research Areas:

Cancer

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Reference:

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127 (2004) "T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells." Holbrook N.J., Smith K.A., Fornace A.J. Jr., Comeau C.M., Wiskocil R.L., Crabtree G.R. Proc. Natl. Acad. Sci. U.S.A. 81:1634-1638 (1984)

Function:

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