人FCGR3B重组蛋白(Fc-gamma RIII-beta

英文名称：

Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B), partial

品名简称：

Recombinant Human FCGR3B protein, partial

货号：

CSB-EP008544HU1

规格:

20μg

价格：

1536

LC-MS/Western Blot：

/

SDS-PAGE：

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

纯度：

Greater than 85% as determined by SDS-PAGE.

内毒素：

Not test

生物活性：

/

基因名：

FCGR3B

Uniprot No.：

O75015

别名：

(Fc-gamma RIII-beta)(CD16-I)(Fc-gamma RIII)(Fc-gamma RIIIb)(FcRIII)(FcRIIIb)(FcR-10)(IgG Fc receptor III-1)(CD antigen CD16b)

种属：

Homo sapiens (Human)

蛋白长度：

Partial

来源：

E.coli

分子量：

47.5 kDa

表达区域：

18-125aa

氨基酸序列：

MRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIH

蛋白标签：

N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged

产品提供形式：

Liquid or Lyophilized powder

缓冲液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

储存条件：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

货期：

13-23 business days

注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

功能1：

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

功能2：

/

文献：

"Analysis of Fc gamma RIII (CD16) membrane expression and association with CD3 zeta and Fc epsilon RI-gamma by site-directed mutation." Lanier L.L., Yu G., Phillips J.H. J. Immunol. 146:1571-1576(1991)

研究领域：

Immunology

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