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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Dog B-lymphocyte antigen CD20 (MS4A1)-VLPs (Active)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Dog B-lymphocyte antigen CD20 (MS4A1)-VLPs (Active)品名简称:
Recombinant Dog MS4A1 protein-VLPs (Active)货号:
CSB-MP661636DO规格:
20μg价格:
3348LC-MS/Western Blot:
/SDS-PAGE:
CSB-MP661636DO is detected by Mouse anti-6*His monoclonal antibody.纯度:
The purity information is not available for VLPs proteins.内毒素:
Less than 1.0 EU/μg as determined by LAL method.生物活性:
Measured by its binding ability in a functional ELISA. Immobilized Dog CD20 at 10 μg/mL can bind Anti-CD20 recombinant antibody (CSB-RA015007MA3HU), the EC50 is 147.3-199.0 ng/mL.基因名:
MS4A1Uniprot No.:
Q3C2E2别名:
(Membrane-spanning 4-domains subfamily A member 1)(CD antigen CD20)种属:
Canis lupus familiaris (Dog) (Canis familiaris)蛋白长度:
Full Length来源:
Mammalian cell分子量:
34.4 kDa表达区域:
1-297aa氨基酸序列:
MTTPRNSMSGTLPVDPMKSPTAMYPVQKIIPKRMPSVVGPTQNFFMRESKTLGAVQIMNGLFHIALGSLLMIHTDVCAPICITMWYPLWGGIMFIISGSLLAAADKNPRKSLVKGKMIMNSLSLFAAISGIIFLIMDIFNITISHFFKMENLNLIKAPMPYVDIHNCDPANPSEKNSLSIQYCGSIRSVFLGVFAVMLIFAFFQKLVTAGIVENEWKKLCSKPKSDVVVLLAAEEKKEQPIETTEEMVELTEIASQPKKEEDIEIIPVQEEEGELEINFAEPPQEQESSPIENDSIP蛋白标签:
C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions)产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex.Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).功能1:
/功能2:
B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.文献:
/研究领域:
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文献和实验membrane, creating a structure similar to an ion channel Delivers early signal in B cell activation, allowing resting B cells to respond to later antigens Rituximab is a chimeric murine-human anti-CD20 antibody used for treatment of B cell
是通过直接或间接地影响到该细胞的bcl-2的表达或功能,进而抑制细胞生长,诱导细胞凋亡,最终得以有效地挟制和杀灭肿瘤,这为抗体可用于联合化疗或降低病人耐药的临床治疗提供了有力的证据。【参考文献】[1]Golay JT,Clark EA,Beverley PC,et al. The CD20 (BP35)antigen is involved in activation of B cell from the G0 to the G1 phase of the cell cycle. J Immunol
Synthesis of a Virus Electrode for Measurement of Prostate Specific Membrane Antigen
. The methods described here utilize electrochemical impedance spectroscopy (EIS) to detect molecular recognition between M13 phage bound to a Au electrode and the following analytes: prostate specific membrane antigen (PSMA), positive and negative control
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