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Monoclonal
human, mouse, rat
发货周期:5-7天
9999
博士德生物
WB, IHC
50μl/100μl/150μl
规格: | 50μl | 产品价格: | ¥1060.0 |
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规格: | 100μl | 产品价格: | ¥1780.0 |
规格: | 150μl | 产品价格: | ¥2580.0 |
货号 | MA00260 |
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产品名称 | Anti-ARNTL Antibody (Clone#OTI1H6) |
基因名 | ARNTL |
抗体来源 | Mouse |
克隆 | OTI1H6 |
抗体亚型 | Mouse IgG1 |
分子量 | 68.5KD |
免疫原 | Full length human recombinant protein of human ARNTL(NP_001169) produced in HEK293T cell. |
内容 | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500 ug/ml |
产品形态 | Liquid |
保存条件 | Stable for 12 months from date of receipt. Store at -20°C as received. |
背景资料 | The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
研究类别 | 1. Hatanaka F, Matsubara C, Myung J, Yoritaka T, Kamimura N, Tsutsumi S, Kanai A, Suzuki Y, Sassone-Corsi P, Aburatani H, Sugano S,Takumi T (Dec 2010). "Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism". Molecular and Cellular Biology. 30 (24): 5636–5648.2. Pappa KI, Gazouli M, Anastasiou E, Iliodromiti Z, Antsaklis A, Anagnou NP (Feb 2013). "The major circadian pacemaker ARNT-like protein-1 (BMAL1) is associated with susceptibility to gestational diabetes mellitus". Diabetes Research and Clinical Practice. 99 (2): 151–7.3. Richards J, Diaz AN, Gumz ML (Oct 2014). "Clock genes in hypertension: novel insights from rodent models". Blood Pressure Monitoring. 19 (5): 249–54. |
Uniprot ID | ARNTL: O00327 |
博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
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Western blot (WB): | 1:4000 |
Immunohistochemistry in paraffin section (IHC): | 1:150 |
*最佳稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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