参考文献 [1] 2017中国城市癌症数据报告 [2]Cook GJ, Pardee TS.Animal models of leukemia: any closer to the real thing? Cancer Metastasis Rev. 2013 Jun;32(1-2):63-76. doi: 10.1007/s10555-012-9405-5. [3] Wang X, Lin Q, Lv F, Liu N, Xu Y, Liu M,Chen Y, Yi Z.LG-362B targets PML-RAR and blocks ATRA resistance of acute promyelocytic leukemia.Leukemia. 2016 Jul;30(7):1465-74. [4] Beurlet S et. al. BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML bytargeting primitive LSK and progenitor cells. Blood. 2013 Oct 17;122(16):2864-76. [5] Kohnken, R., Porcu, P. & Mishra, A. Overview of the Use of Murine Models in Leukemia and Lymphoma Research. Frontiers in oncology 7, 22 (2017). [6] Mc Cormack, E., Bruserud, O., & Gjertsen, B. T. Animal models of acute myelogenous leukaemia— development, application and future perspectives. Leukemia, 19, 687-706(2005). 服务内容: 裸鼠的购买,饲养,造模、取材,和后续指标的检测等。 肿瘤模型(皮下移植瘤、原位癌): 乳腺癌 肺癌 结肠癌 胃癌 肝癌 白血病 淋巴瘤 皮肤癌 前列腺癌 食管癌 宫颈癌 卵巢癌 人绒毛膜癌 口腔癌 肾癌 膀胱癌 胰腺癌 大肠癌 交付标准: 整套的动物模型构建,动物饲养,标本采集和指标检测的实验服务,提供详细的动物实验报告单。