- ￥1700 - 4000
- GeneTex
- 美国
- GTX135384
- 2025年07月11日
- WB, ICC/IF, ELISA
- Rabbit
- SARS Coronavirus 2
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 Spike (S1) (SARS-CoV-2 (strain Wuhan-Hu-1)). The exact sequence is proprietary.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
SARS Coronavirus 2
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
SARS Coronavirus 2
- 目录编号：
GTX135384
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB, ICC/IF, ELISA
- 浓度：
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
This antibody detects SARS-CoV-2 Spike protein, but does not cross-react with SARS-CoV or MERS-CoV spike proteins based on our internal testing.
- 抗体英文名：
SARS-CoV-2 (COVID-19) Spike S1 antibody
- 抗体名：
SARS-CoV-2 (COVID-19) Spike S1 抗体
- 规格：
100 μl/25 μl
| 规格： | 100 μl | 产品价格： | ￥4000.0 |
|---|---|---|---|
| 规格： | 25 μl | 产品价格： | ￥1700.0 |
Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with SARS-CoV-2 (COVID-19) Spike antibody (GTX135384) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
SARS-CoV-2 (COVID-19) Spike antibody detects SARS-CoV-2 (COVID-19) Spike protein by immunofluorescent analysis.
Sample: Mock and SARS-CoV-2 Spike-transfected 293T cells were fixed in 4% PFA at RT for 15 min.
Green: SARS-CoV-2 (COVID-19) Spike stained by SARS-CoV-2 (COVID-19) Spike antibody (GTX135384) diluted at 1:1000.
Blue: Fluoroshield with DAPI (GTX30920).
Indirect ELISA analysis performed by coating plate with recombinant SARS-CoV-2 (COVID-19) Spike S1 protein, His tag (active) protein (GTX01554-pro) (4000-62.5 ng/mL). Coated protein probed with SARS-CoV-2 (COVID-19) Spike S1 antibody (GTX135384) (1 μg/mL). Rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) detected bound primary antibody.
Indirect ELISA analysis performed by coating plate with recombinant SARS-CoV-2 (COVID-19) Spike S1 protein, His tag (active) protein (GTX135817-pro) (4000-62.5 ng/mL). Coated protein probed with SARS-CoV-2 (COVID-19) Spike S1 antibody (GTX135384) (1 μg/mL). Rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) detected bound primary antibody.
Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with SARS-CoV-2 (COVID-19) Spike antibody (GTX135384) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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文献和实验Narayanan A et al., Commun Biol 2022 (PMID:35217718)
COVID-19 infection. Nature Scientifc Reports 2:MacMullan,MA et al. (2020) ELISA detection of SARS-CoV-2 antibodies in saliva. Nature Scientifc Reports 3:Hettegger,P et al. (2019) High similarity of IgG antibody profles in blood and saliva opens
Cell Death Differ：中大五院黄曦团队发现新冠病毒引起肺损伤的分子机制
近期，中山大学附属第五医院黄曦团队报道了 SARS-CoV-2 的 membrane (M) 蛋白通过靶向并抑制胞内 BOK 的泛素化降解，激活肺上皮细胞线粒体凋亡途径而引起肺损伤，该发现为 COVID-19 的靶向治疗提供了潜在靶点。 图片来源：Cell death & differentiation SARS-CoV-2 感染已经导致全球数以百万人的死亡，其中大部分死亡患者出现呼吸困难，肺部出现大量凋亡的细胞和渗漏的粘液，已有研究证实 SARS-CoV-2 感染引起肺细胞凋亡参与上述
日前，北京大学生命科学学院魏文胜课题组在 Cell 杂志上在线发表题为“Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants”的研究论文。 魏文胜团队首先建立了体外高效制备高纯度环状 RNA 的技术平台，针对新型冠状病毒及其变异株，设计了编码新冠病毒刺突蛋白（Spike）受体结构域（RBD）的环状 RNA 疫苗。 该项研究中制备的针对新冠病毒德尔塔变异株的环状 RNA 疫苗（circRNARBD
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