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- 2025年07月11日
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9026-30-6
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100U///500U
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Poly(A) polymerase
CAS No. : 9026-30-6
MCE 国际站：Poly(A) polymerase
产品活性：Poly(A) polymerase 以催化 ATP 以 AMP 的形式依次掺入到 RNA 3'末端，即在 RNA3'端加多聚腺苷尾。Poly(A) polymerase 能够提高 RNA 的稳定性并提高 mRNA 在真核细胞中的翻译效率。Poly(A) polymerase 具有很高的加尾效率，能够在 RNA 3'端加入 20-200 个 A 碱基。
研究领域：Cell Cycle/DNA Damage
作用靶点：DNA/RNA Synthesis
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文献和实验Activity Assays for Poly-ADP Ribose Polymerase
Poly(ADP-ribose) polymerase (PARP-1) is a nuclear enzyme that has traditionally been thought to require discontinuous or “damaged” DNA (dcDNA) as a coenzyme, a preconception that has limited research mainly to its role in cell pathology, i.e
Markers of Poly (ADP-Ribose) Polymerase Activity as Correlates of DNA Damage
Poly (ADP-ribose) polymerase (PARP-1; EC 2.4.2.30) is a predominantly nuclear enzyme long presumed to function in the identification and repair of DNA strand nicks and breaks (for recent reviews see: 1 –3 ). PARP is comprised of a N
, the proteins were solubilized with different methods, and the affinity chromatography on NAD-Agarose of the first protocol was replaced by a gel filtration step in the second protocol. When enzyme activity was compared with electrophoresis and anti-poly-ADP
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