HUP30

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HUP30

CAS No. : 312747-21-0

MCE 国际站：HUP30

产品活性：HUP30 是一种血管扩张剂。HUP30 刺激可溶性鸟苷酸环化酶的产生，激活 K⁺ 通道，并阻断细胞外 Ca²⁺ 流入。

研究领域：Membrane Transporter/Ion Channel  |  Neuronal Signaling

作用靶点：Potassium Channel  |  Calcium Channel

In Vitro: HUP30 inhibits Phenylephrine-induced aorta contraction with an IC₅₀ value of 3.9 μM.
HUP30 (100 μM) increases cGMP levels in Phenylephrine-stimulated aorta.
HUP30 causes an antispasmodic effect on rat aorta rings contracted by 25/30 mM K⁺, with an IC₅₀ value of 7.5 μM.
HUP30 (3-100 μM) inhibits both extracellular Ca²⁺ influx and Ca²⁺ mobilization induced by Phenylephrine.
HUP30 (10-100 μM) inhibits the current in single tail artery myocytes.

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