- ￥960 - 1600
- Solarbio
- 北京
- K000359P
- 2026年02月13日
- Rabbit
- Human Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human MSR1
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 适应物种：
Human Mouse
- 目录编号：
K000359P
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 靶点：
MSR1
- 抗体英文名：
Anti-MSR1 Polyclonal Antibody
- 抗体名：
CD204;SCARA1;SR-A;SR-AI;SR-AII;SR-AIII;SRA;phSR1;phSR2
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 英文名称 | Anti-MSR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD204;SCARA1;SR-A;SR-AI;SR-AII;SR-AIII;SRA;phSR1;phSR2;macrophage scavenger receptor 1 |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
| 蛋白分子量 | 50kDa |
| Gene ID | 4481 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MSR1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MSR1 |
| 亚细胞定位 | Membrane Single-pass type II membrane protein |
| Swiss Prot | P21757 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. |
| 应用 | WB IHC IF |
| 交叉反应 | Human Mouse |
| 规格 | 50ul 100ul |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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