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文献和实验Methods for the Analysis of HIV-1 Nucleocapsid Protein Interactions with Oligonucleotides
HIV-1 Nucleocapsid protein (NC) is a small basic protein that contains two retroviral zinc fingers. It is a highly effective nucleic acid chaperone that plays a critical role in viral replication acting as a cofactor in reverse transcription
instrumentation was used to monitor binding reactions between HSP72 and naturally occurring sequence variants of the measles virus (MV) nucleocapsid protein (N), a structural protein regulating transcription/replication of the viral genome. Binding reactions
Cell Death Differ:中大五院黄曦团队发现新冠病毒引起肺损伤的分子机制
病理发生。然而,SARS-CoV-2 感染引起肺细胞凋亡的机制仍不清楚。 2022 年 1 月 13 日,中山大学附属第五医院黄曦课题组在 Cell death & differentiation 上发表了题为 SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK 研究性论文。该研究证实了病毒膜(M)蛋白会通过靶向 BOK 分子,介导肺
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