重组小鼠表皮膜蛋白1

重组小鼠表皮膜蛋白1相关信息：

英文名称
Recombinant mouse EMP-1 protein, GST & His
中文名称
重组小鼠表皮膜蛋白1
英文别名
CL-20; EMP 1; EMP1; EMP1_HUMAN; Epithelial membrane protein 1; Protein B4B; TMP; Tumor-associated membrane protein; Recombinant mouse EMP-1 protein, GST & His
蛋白细胞定位
细胞膜
分子量
17
浓度
＞0.5 mg/ml
储存液
4 M Urea (pH=9.0)
保存条件
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.

重组小鼠表皮膜蛋白1

背景资料：Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.

重组小鼠表皮膜蛋白1应用：仅供研究使用，不用于临床诊断！




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