产品名称:Human TIGIT Antibody (Etigilimab, Research Use)
产品编号:NBR-0889
针对靶点:TIGIT
抗体药商品名:Etigilimab
抗体药描述:Etigilimab is an IgG1 monoclonal antibody which binds to the human TIGIT receptor on immune cells with a goal of improving the activation and effectiveness of T-cell and NK cell anti-tumor activity.
Gene Name: TIGIT
Synonyms: DKFZp667A205; FLJ39873; VSIG9; VSTM3
Target Description: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Ensembl: ENSG00000181847
Uniprot: Q495A1