产品名称:Human Sclerostin Antibody (Romosozumab, Research Use)
产品编号:NBR-0280
针对靶点:Sclerostin
抗体药商品名:Romosozumab
抗体药描述:Romosozumab is a monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture, patients who are intolerant of other treatments, or patients who have failed other treatments.
Gene Name: Sclerostin
Synonyms: DAND6; VBC
Target Description: HMay be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
Ensembl: ENSG00000167941
Uniprot: Q9BQB4