重组人程序性死亡1（CD279）蛋白

重组人程序性死亡1（CD279）蛋白相关信息：

英文名称	Recombinant human PD-1 protein, His
中文名称	重组人程序性死亡1（CD279）蛋白
别    名	CD279; CD279 antigen; hPD 1; hPD l; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Programmed cell death protein 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2; Recombinant human PD-1 protein, His
理论分子量	17.57kDa
检测分子量	17 kDa
性    状	Lyophilized or Liquid
浓    度	＞0.5 mg/ml
物    种	Human
序    列	21-170/288
纯    度	>95% as determined by SDS-PAGE
纯化方法	AC
内毒素	Not analyzed
表达系统	E.coli
活性	Not tested
标签	His
缓 冲 液	20 mM Tris-HCl (pH=9.0) with 8 M Urea
保存条件	Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

重组人程序性死亡1（CD279）蛋白

产品介绍：This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
CD279 is an immunoglobulin superfamily member, also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes, and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands, PDL1 (also known as B7H1) and PDL2 (B7DC), are members of the B7 immunoglobulin superfamily.

重组人程序性死亡1（CD279）蛋白应用：仅供研究使用，不用于临床诊断！




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