重组人C反应蛋白

重组人C反应蛋白相关信息：

理论分子量	23kDa
检测分子量	25 kDa
性    状	Lyophilized or Liquid
浓    度	＞0.5 mg/ml
物    种	Human
序    列	19-224/224
纯    度	>95% as determined by SDS-PAGE
纯化方法	AC
内毒素	Not analyzed
表达系统	E.coli
活性	Yes
标签	C-His
缓 冲 液	10 mM TBS (pH=7.4)
保存条件	Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

重组人C反应蛋白

产品介绍：C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.

重组人C反应蛋白应用：仅供研究使用，不用于临床诊断！




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