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- SIGMA
- 美国
- P7888-250MG
- 2025年07月06日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
−20°C
- 保质期：
/
- 英文名：
DL-Propargylglycine
- 库存：
999
- 供应商：
麦格生物
- CAS号：
64165-64-6
- 规格：
P7888-250MG
说明
应用
Metabolic Labeling Strategy Boosted Antibacterial Efficiency for Photothermal and Photodynamic Synergistic Bacteria-Infected Wound Therapy.: This study demonstrates the enhanced antibacterial efficiency of a metabolic labeling strategy using ᴅʟ-Propargylglycine in photothermal and photodynamic therapy for treating bacteria-infected wounds (Li et al., 2022).
Metabolic Labeling of Peptidoglycan with NIR-II Dye Enables In Vivo Imaging of Gut Microbiota.: This research utilizes ᴅʟ-Propargylglycine for metabolic labeling, allowing near-infrared II imaging of gut microbiota in vivo, providing new insights into microbiome studies (Wang et al., 2020).
Hydrogen sulfide upregulated mRNA expressions of sodium bicarbonate cotransporter1, trefoil factor1 and trefoil factor2 in gastric mucosa in rats.: Investigates the role of ᴅʟ-Propargylglycine, in upregulating specific mRNA expressions in gastric mucosa, with implications for gastrointestinal research (Cheraghi et al., 2016).
生化/生理作用
DL-丙炔甘氨酸（PAG）是胱硫醚γ-裂解酶（GCL）的不可逆抑制剂，该酶是一种参与谷胱甘肽合成[1] 和调节同型半胱氨酸浓度并介导半胱氨酸合成的代谢转硫途径的关键酶。[2]利用PAG治疗动物疾病模型显示其可减轻破坏 （H2S）形成或作用的疾病的相关症状。[3][4]
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文献和实验Vitamin B-6 deficiency suppresses the hepatic transsulfuration pathway but increases glutathione concentration in rats fed AIN-76A or AIN-93G diets.
Carolina P Lima et al.
The Journal of nutrition, 136(8), 2141-2147 (2006-07-22)
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