- ￥1200
- 万类生物
- 中国
- WL03144
- 2025年12月04日
- WB,IHC,IF
- 兔
- HMR
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- 详细信息
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
多克隆
- 标记物：
无
- 适应物种：
HMR
- 保质期：
一年
- 抗原来源：
兔
- 供应商：
万类生物
- 宿主：
兔
- 应用范围：
WB,IHC,IF
- 浓度：
＞1 mg/ml
- 抗体英文名：
ATG12 antibody
- 抗体名：
ATG12 抗体
- 规格：
50μl(>50μg)
产品概述
Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Atg12 (autophagy-related protein 12), also known as APG12, APG12L, FBR93 or HAPG12, is a 140 amino acid protein that is ubiquitously expressed and belongs to the Atg12 family of proteins. Atg12 is a homolog of the yeast protein Apg12 that participates in autophagy. in humans, Atg12 is essential for autophagy and localizes to the cytoplasm where it is covalently bound to APG5, a conjugation reaction that requires APG7, Atg10 and ATP. The Atg12-APG5 conjugate functions as an important regulator of the autophagic process and is required for the change in membrane morphology and development of autophagosomes.
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