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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 亚型:
IgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
多克隆
- 标记物:
无
- 适应物种:
HMR
- 保质期:
一年
- 抗原来源:
兔
- 供应商:
万类生物
- 宿主:
兔
- 应用范围:
WB,IHC
- 浓度:
>1 mg/ml
- 抗体英文名:
Androgen Receptor antibody
- 规格:
50μl(>50μg)
产品概述
The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Androgen receptors (AR) have been found in a variety of tissues, including reproductive organs, central nervous system and skeletal muscle.
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文献和实验Analysis of Androgen Receptor SUMOylation
Androgen receptor (AR) is a ligand-controlled transcription factor that is deregulated and therefore targeted in prostate cancer. In addition to androgens, AR is regulated by post-translational modifications (PTMs). SUMOylation, conjugation
In Vitro and In Vivo Silencing of the Androgen Receptor
The androgen receptor (AR) plays a pivotal role in the progression of prostate cancer from the androgen-dependent to the castration-resistant state, making it a potential target for therapy. In this chapter, we describe the preparation
Analysis of Interdomain Interactions of the Androgen Receptor
High-affinity binding of testosterone or dihydrotestosterone to the androgen receptor (AR) triggers the androgen-dependent AR NH2 - and carboxyl-terminal (N/C) interaction between the AR NH2 -terminal FXX LF motif and the activation function
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