- ￥1200
- 万类生物
- 中国
- WL03233
- 2025年11月20日
- WB,IHC,IF
- 兔
- HMR
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- 详细信息
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
多克隆
- 标记物：
无
- 适应物种：
HMR
- 抗原来源：
兔
- 供应商：
万类生物
- 宿主：
兔
- 应用范围：
WB,IHC,IF
- 抗体英文名：
STAT6 antibody
- 规格：
50μl(＞50μg)
产品概述
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Stat6 is activated via phosphorylation at Tyr641 and is required for responsiveness to IL-4 and IL-13. In addition, Stat6 is activated by IFN-α in B cells, where it forms transcriptionally active complexes with Stat2 and p48. Protein phosphatase 2A is also involved in regulation of IL-4-mediated Stat6 signaling.
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