Anti-RUNX1T1 Polyclonal Antibo

产品简介

英文名称	Anti-RUNX1T1 Polyclonal Antibody
宿主	Rabbit
别名	AML1-MTG8; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2; protein CBFA2T1
稀释比例	WB 1:8000-12000.
蛋白分子量	68/64/48/45kDa
Gene ID	862
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.11.
纯化方法	Octanoic acid-ammonium sulfate precipitation
亚型	IgG
免疫原	A synthetic peptide of human RUNX1T1
亚细胞定位	Nucleus
Swiss Prot	Q06455
背景资料	This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Public Immunogen Range	5-55/604aa
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with RUNX1T1 antibody diluted at 1:10000;Lane: SH-SY5Y,Mouse brain