Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位
Nucleus Cytoplasm
免疫原
A synthetic peptide of human ATM
亚型
IgG
性状
液体
纯化方法
Affinity purification
背景资料
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Public Immunogen Range
A synthetic peptide of human ATM
克隆类型
Polyclonal Antibody
交叉反应
Human
应用
WB
规格
50ul 100ul
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with ATM antibody diluted at 1:1000