Endothelin B Receptor Like Protein 2;Endothelin B receptor-like protein 2;ETBR LP 2;ETBR-LP-2;ETBR2_HUMAN;ETBRLP2;G protein coupled receptor 37 like 1;G-protein coupled receptor 37-like 1;Gpr37l1
背景资料
G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activit. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.
Swiss Prot
O60883
Gene ID
9283
亚细胞定位
Cell membrane
宿主
Rabbit
克隆类型
Polyclonal Antibody
亚型
IgG
蛋白分子量
53kDa
稀释比例
WB 1:1000-3000.
免疫原
A synthetic peptide of human GPR37L1
Public Immunogen Range
5-55/481aa
纯化方法
Octanoic acid-ammonium sulfate precipitation
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4.
保存
Store at -20°C. Avoid freeze / thaw cycles.
交叉反应
Human
应用
WB
规格
50ul 100ul
单位
支
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with GPR37L1 antibody diluted at 1:2000;Lane: MDA-MB-231.