- ￥960
- Solarbio
- K111579P
- 北京
- 2025年12月16日
- IHC
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
TAOK1
- 应用范围：
IHC
- 宿主：
Rabbit
- 适应物种：
Human;Mouse;Rat
- 保质期：
一年
- 供应商：
北京索莱宝科技有限公司
- 克隆性：
Polyclonal Antibody
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 亚型：
IgG
- 免疫原：
A synthetic peptide of human TAOK1
- 规格：
50ul
| 英文名称 | Anti-TAOK1 Polyclonal Antibody |
| 靶标 | TAOK1 |
| 别名 | 2810468K05Rik, AU020252, D130018F14Rik, EC 2.7.11.1, FLJ14314, hKFC B, hKFC-B, KIAA1361, Kinase from chicken homolog B, MAP3K16, MARK kinase, MARKK, MGC29021, Microtubule affinity regulating kinase kinase, mKIAA1361, Prostate-derived sterile 20-like kinase 2, PSK2, Serine/threonine kinase TAO1, Serine/threonine protein kinase TAO1, Serine/threonine protein kinase TAO1 homolog, Serine/threonine-protein kinase TAO1, STE20 like kinase, STE20 like kinase PSK2, STE20-like kinase PSK2, TAO kinase 1, Taok1, TAOK1_HUMAN, Thousand and one amino acid protein 1 |
| 背景资料 | Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade. |
| Swiss Prot | Q7L7X3 |
| Gene ID | 57551 |
| 亚细胞定位 | Cytoplasm |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 预测交叉反应 | Xenopus laevis |
| 蛋白分子量 | 46/97/116kDa |
| 稀释比例 | IHC 1:50-200. |
| 免疫原 | A synthetic peptide of human TAOK1 |
| Public Immunogen Range | 415-465/1001aa |
| 纯化方法 | Affinity purification |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 交叉反应 | Human;Mouse;Rat |
| 应用 | IHC |
| 规格 | 50ul 100ul |
| 单位 | 支 |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Immunohistochemistry of paraffin-embedded Human breast cancer with TAOK1 antibody diluted at 1:100.
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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