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文献和实验The Immortalization of Human Endometrial Cells
The loss of replicative potential with each cell division has been attributed to the progressive shortening of telomeres. This “mitotic clock” occurs because most normal human cells are telomerase-negative. Telomerase is a multicomponent
三句话读懂一篇 CNS:补硒提高免疫力又添新证据;张锋开发新
峰、刘蔡钺教授团队,在 Nature Aging 杂志上在线发表了研究论文 A stress-induced miR-31–CLOCK–ERK pathway is a key driver and therapeutic target for skin aging。该研究通过小鼠模型研究、转录组分析和谱系追踪分析,发现 miR-31–CLOCK–ERK 信号通路被基因组损伤或物理损伤激活,进而驱动皮肤上皮组织衰老的关键分子机制,提供了具有临床潜力的靶向干预途径,为人类永葆青春的梦想再添利器!图
Measurement of Melatonin and 6-Sulphatoxymelatonin
Melatonin and its major metabolite, 6-sulphatoxymelatonin, can routinely be measured by RIA or ELISA. Plasma, serum or saliva samples maybe used for melatonin measurement and urine for the metabolite. Melatonin is a hormone produced
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