It has been known for decades that the tumor extracellular matrix (ECM) is dysfunctional leading to loss of tissue architecture and promotion of tumor growth. The altered ECM and tumor fibrogenesis leads to tissue stiklness that act as a physical barrier to immune cell infiltration into the tumor microenvironment (TME). It is becoming
It has been known for decades that the tumor extracellular matrix (ECM) is dysfunctional leading to loss of tissue architecture and promotion of tumor growth. The altered ECM and tumor fibrogenesis leads to tissue stiklness that act as a physical barrier to immune cell infiltration into the tumor microenvironment (TME). It is becoming