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文献和实验Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity
of interest binds the N -methyl-d -aspartate receptor (NMDAR), a receptor for glutamate that is a major excitatory neurotransmitter in the brain involved in synaptic plasticity, in memory and learning, and in emotional responses. We introduce basic
Engineering the NMDA Receptor Channel Lining
Neurotransmitter-gated channels, such as the NMDA receptor, are oligomeric membrane proteins assembled from multiple homologous subunits organized around a central ion-conducting pore (1 ,2 ). A major effort is directed toward understanding
High-Throughput Functional Detection of NMDA Receptor Activity
target protein. The heterologous expression of cloned receptor proteins in defined cell lines provides the specificity of the interaction.
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