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文献和实验Generation of Parabiotic Mice for the Study of DC and DC Precursor Circulation
Dendritic cells (DCs) are the main regulators of adaptive immune responses and considerable interest currently focuses on the mechanisms of DC homeostasis. Understanding the mechanisms and regulation of DC generation may provide cues
Determination of DC-SIGN and DC-SIGNR Repeat Region Variations
DC-SIGN and DC-SIGNR efficiently bind HIV-1 and other viral as well as nonviral pathogens and assist either cis or trans infection. Both are type II transmembrane proteins that consist of an N-terminal cytoplasmic domain, a repeat region
实验原理 Add a mixture of biotinylated monoclonal antibodies against non-DC cells to your starting sample. Add Depletion MyOne™ SA Dynabeads® and allow them to bind to the non-DCs during a short incubation. Separate
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