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说明书
说明书
说明书
多克隆
Rabbit
说明书
HOXA13
同源异型盒基因HOXA13抗体
Unconjugated
说明书
说明书
KLH conjugated synthetic peptide derived from Human HOXA13
LgG
液体
说明书
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
1mg/ml
100ul
产品名称:同源异型盒基因HOXA13抗体 英文名称:HOXA13 英文别名:Homeo box 1J; Homeo box A13; Homeobox 1J; Homeobox A13; Homeobox protein Hox A13; Homeobox protein Hox-1J; Homeobox protein Hox-A13; Homeobox protein HOXA13; Homeobox1J; HomeoboxA13; HOX 1; HOX 1J; Hox 1J protein; HOX A13; HOX1; HOX1J; HOXA 13; HOXA13; HXA13_HUMAN; Transcription factor HOXA13. 交叉反应: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原: KLH conjugated synthetic peptide derived from Human HOXA13 蛋白细胞定位: 细胞核 纯化方法: affinity purified by Protein A 亚型: IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 背景资料: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. HoxA13 and HoxD13 also bind to other BMP and TGF-beta/Activin-regulated Smad proteins including Smad1 and Smad2, but not Smad4. In humans and mice, loss of HOXA13 function causes defects in the growth and patterning of the digits and interdigital tissues. Analysis of HoxA13 expression reveals a pattern of localization overlapping with sites of reduced Bmp2 and Bmp7 expression in HoxA13 mutant limbs. HoxA13 regulates Bmp2 and Bmp7 expression, providing a link between HoxA13, its target genes and the specific developmental processes affected by loss of HoxA13 function. |
产品名称 | 浓度 | 型号 |
同源异型盒基因HOXA13抗体 | 1mg/ml | EY-01K1107 |
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