Rad51 (DGR18573) Rabbit mAb产品图

Rad51 (DGR18573) Rabbit mAb

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  • ¥398
  • 戴格
  • 浙江杭州
  • 2026年10月15日
  • WB, IHC-P, ICC/IF, FC, IP
  • Rabbit
  • Human,Mouse,Rat
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    • 详细信息
    • 技术资料
    • 免疫原:

      A synthetic peptide of human Rad51

    • 亚型:

      IgG

    • 保存条件:

      Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

    • 克隆性:

      Monoclonal

    • 适应物种:

      Human,Mouse,Rat

    • 库存:

      99

    • 宿主:

      Rabbit

    • 应用范围:

      WB, IHC-P, ICC/IF, FC, IP

    • 靶点:

      Rad51

    • 规格:

      10μl

    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

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