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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
DS45500853
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2735803-28-6
- 规格:
2 mg/1 mL
| 规格: | 2 mg | 产品价格: | ¥1380.0 |
|---|---|---|---|
| 规格: | 1 mL | 产品价格: | ¥2280.0 |
Product Introduction
Bioactivity
英文名:DS45500853
描述:DS45500853, an estrogen-related receptor α (ERRα) agonist, acts as an inhibitor of the binding interaction between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM), exhibiting an IC50 of 0.80 μM. This compound holds potential for research pertaining to metabolic disorders, particularly type 2 diabetes mellitus (T2DM).

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文献和实验EMSA using ds Oligonucleotides
Solutions 10X Annealing Buffer 200 mM Tris 8.0 200 m l 1M Tris pH 8.0 10 mM EDTA 8.0 20 m l .5M EDTA pH 8.0 500 mM NaCl 100 m l 5M NaCl 280 m l Q store at room temperature 10X Klenow Buffer 500 mM Tris 7.5 500 m l 1
EMSA using ds Oligo nucleotides
Solutions Procedure Design complementary oligonucleotides with compatible half sites
Transposon Tagging with AC/Ds in Arabidopsis
(2 ‐5 ). In Arabidopsis, Actzvator/Dissoclation (AC/ Ds) have been used to isolate recessive loss-of-function mutations (6 —8 ), dommant gain of function mutations (9 ) and to isolate genes based on then patterns of expression (10 ,11 ).
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