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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
HR22C16
- 库存:
10
- 供应商:
TargetMol
- CAS号:
462630-41-7
- 规格:
100 mg/25 mg/50 mg
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
Product Introduction
Bioactivity
英文名:HR22C16
描述:HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.

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文献和实验反射可引出。 串联质谱新生儿遗传代谢病筛查发现:游离肉碱(C0)显着降低, 2.95 umol/L,(参考范围:9.5~40 umol/L);C0/(C16+C18)=1.18(参考范围:5~36)。复查 C0 =2.83 umol/L ,C16 = 0.1 umol/L,C18 =0.08 umol/L, C18:1 =0.07 umol/L, 均显着降低。考虑原发肉碱缺乏症可能性大。基因突变分析显示该宝宝 SLC22A5 基因存在 c.288del G 和 c.1400 C>G 复合杂合
Thrombin Cleavage of GST-Fusion protein
activity keeps the enzyme in aliquots at -80°C. Thrombin (MW 37kDa) ~4500units/mg. One unit cleaves theoretical 100ug protein in 16hr at 22°C in buffer. Another possibility is to use high purity enzyme from Sigma # T-6884: 3-10 U of thrombin can be used
Factor Xa Cleavage of MBP-Fusion protein
BioLabs cleaves theoretical 100ug fusion protein in 16hr at 22°C in buffer. You can incubate enough eluate to see on PAGE-SDS gels (~3ug) with 0.01, & 0.03 ug of Factor Xa 2hr, 4hr, 6hr & ON at 22°C (or RT). Stop the reaction with PAGE-SDS sample buffer
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