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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
IL33抗体
- 抗体英文名：
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- 靶点：
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- 浓度：
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- 应用范围：
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- 宿主：
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- 适应物种：
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- 保质期：
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- 抗原来源：
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- 目录编号：
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- 级别：
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- 库存：
现货
- 供应商：
爱必信(上海)生物科技有限公司
- 标记物：
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- 克隆性：
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- 保存条件：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
- 形态：
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- 亚型：
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- 免疫原：
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- 规格：
50ug/100ug
| 规格： | 50ug | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥2300.0 |
| 别名 | IL33抗体;C9orf26, CHROMOSOME 9 OPEN READING FRAME 26, DKFZp586H0523, DVS27, DVS27 related protein, IL 1F11, IL 33, IL-1F11, IL-33, IL1F11, IL33, IL33_HUMAN, Interleukin 1 family member 11, Interleukin 33, INTERLEUKIN 33 NFHEV, Interleukin 33 precursor, Interleukin-1 family member 11, Interleukin-33 (109-270), Interleukin33, NF HEV, NF-HEV, NFEHEV, NFHEV, Nuclear factor for high endothelial venules, Nuclear factor from high endothelial venules, OTTHUMP00000021041, RP11 575C20.2, |
| 宿主 | Rabbit |
| 特异性 | IL33 Antibody detects endogenous levels of total IL33. |
| 反应种属 | Human;Mouse;Rat |
| 应用 | WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000 |
| 分子量 | Predicted molecular weight: 31kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 | A synthesized peptide derived from Human IL33(Accession O95760), corresponding to amino acid residues K155-M183. |
| 浓度 | 1mg/ml |
| 纯化方法 | The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin . |
| 类型 | Polyclonal Antibody |
| 储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| 存储溶液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
| 背景说明 | Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528). |
| 组织特异性 | Expressed at high level in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes. Almost undetectable in placenta. |
| 翻译后修饰 | The full-length protein can be released from cells and is able to signal via the IL1RL1/ST2 receptor. However, proteolytic processing by CSTG/cathepsin G and ELANE/neutrophil elastase produces C-terminal peptides that are more active than the unprocessed full length protein. May also be proteolytically processed by calpains (PubMed:19596270). Proteolytic cleavage mediated by apoptotic caspases including CASP3 and CASP7 results in IL33 inactivation (PubMed:19559631). In vitro proteolytic cleavage by CASP1 was reported (PubMed:16286016) but could not be confirmed in vivo (PubMed:19465481) suggesting that IL33 is probably not a direct substrate for that caspase. |
| 细胞定位 | Cytosol;Extracellular region or secreted;Nucleus; |
| UniProt | O95760 |
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文献和实验- House Dust Mite Induces IL-33 Release From Human Nasal Epithelial Cells via P2Y Purinergic Signals and ERK/P38 MAPK PathwaysBin Liu, Pei Zhou, Tingting Feng, Jiping Li
Research Square. 2021 Jul 13 .
- House Dust Mite Induces IL-33 Release From Human Nasal Epithelial Cells via P2Y Purinergic Signals and ERK/P38 MAPK Pathways.Bin Liu,Pei Zhou,Tingting Feng,Jiping Li
reach square.
- House Dust Mite Induces IL-33 Release From Human Nasal Epithelial Cells via P2Y Purinergic Signals and ERK/P38 MAPK Pathways.Bin Liu,Pei Zhou,Tingting Feng,Jiping Li
reach square.
Immunofluorescence: Rabbit Anti-Murine RELMα
for 25 minutes. 3. Incubate the tissue section with blocking buffer for 20 minutes. 4. Incubate the tissue section overnight at 4?C with Rabbit Anti-Murine RELMα at 4.0 ng/mL in 1X PBS with 0.01% Triton-X and 0.5% BSA. Wash the slide
抗核抗体(anti-nucleic antibody，ANA)检测
抗核抗体(anti-nucleic antibody，ANA)是以真核细胞的核成分为靶抗原的自身抗体的总称。细胞核内含有许多不同成分如核蛋白、核糖核蛋白(ribonucleo protein，RNP)、脱氧核糖核酸(DNA)等。 在某些因素，如细菌、病毒、药物等作用下，可改变细胞核某些成分的性质，激发机体免疫系统产生许多抗不同核成分的抗体。
Polyclonal Antibody Production
Zealand White Rabbits and have them delivered to the ARC. Don’t put all your eggs in one basket only using one rabbit. Let them get accustomed to there home there for two weeks before the first pre-bleed. Pre-bleed
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