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- 技术资料
- 抗体名:
IL-17抗体
- 抗体英文名:
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- 靶点:
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- 浓度:
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- 应用范围:
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- 宿主:
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- 适应物种:
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- 保质期:
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- 抗原来源:
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- 目录编号:
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- 级别:
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- 库存:
现货
- 供应商:
爱必信(上海)生物科技有限公司
- 标记物:
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- 克隆性:
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- 保存条件:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
- 形态:
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- 亚型:
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- 免疫原:
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- 规格:
100ul/50ul
| 规格: | 100ul | 产品价格: | ¥2300.0 |
|---|---|---|---|
| 规格: | 50ul | 产品价格: | ¥1500.0 |
| 别名 | IL-17抗体;Interleukin-17, CTLA 8, CTLA8, Cytotoxic T lymphocyte associated antigen 8, Cytotoxic T lymphocyte associated protein 8, Cytotoxic T lymphocyte associated serine esterase 8, IL 17A, IL17A, IL-17A, Interleukin 17, Interleukin 17A, Interleukin17, Interleukin17A. , , |
| 宿主 | Rabbit |
| 特异性 | IL-17 |
| 反应种属 | Mouse;Rat; |
| 应用 | WB=1:500-2000 |
| 分子量 | Predicted molecular weight: 15kDa Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse IL-17 (85-150aa):85-150/150 |
| 浓度 | 1mg/ml |
| 纯化方法 | affinity purified by Protein A |
| 类型 | Polyclonal Antibody |
| 同种型 | IgG |
| 储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 存储溶液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 研究领域 | 肿瘤 细胞生物 免疫学 转录调节因子 |
| 背景说明 | IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17. |
| 细胞定位 | 分泌型蛋白 |
| UniProt | Q16552 |
Sample: Intestine (Rat)cell Lysate at 40 ug
Primary: Anti-IL-17(abs121447)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 15 kD
Observed band size: 19kD
Sample:Blood (mouse)cell Lysate at 40 ug
Primary: Anti-IL-17(abs121447)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 15 kD
Observed band size: 19kD
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文献和实验- Pain Relief Dependent on IL-17–CD4+ T Cell–β-Endorphin Axis in Rat Model of Brachial Plexus Root Avulsion After Electroacupuncture TherapyZihang Xu, Yangzhuangzhuang Zhu, Jun Shen, Lin Su, Yifei Hou, Mingxi Liu, Xiaoning Jiao, Xiao Chen, Shiguo Zhu, Yechen Lu, Chao Yao, Lixin Wang, Chenyuan Gong, Zhenzhen Ma, Chunpu Zou, Jianguang Xu
Frontiers in Neuroscience. 2021 Feb 09 .
影响因子: 3.94
- Human Umbilical Mesenchymal Stem Cells Display Therapeutic Potential in Rheumatoid Arthritis by Regulating Interactions Between Immunity and Gut Microbiota via the Aryl Hydrocarbon ReceptorXiaoya Li, Cheng Lu, Danping Fan, Xiangchen Lu, Ya Xia, Hongyan Zhao, Huihui Xu, Yongliang Zhu, Jingtao Li, Honglin Liu, Cheng Xiao
Front Cell Dev Biol. 2020 Mar 13 .
影响因子: 5.206
人 白细胞介素17(IL-17) 酶联免疫 分析( ELISA ) 试剂 盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中 白细胞介素17(IL-17)的 含量。 实验原理 : 本试剂盒应用 双抗体 夹心法测定 标本 中 人白细胞介素 -1 7( IL-1 7) 水平。用纯化的 人白细胞介素 -1 7( IL-1 7)抗体 包被微孔板,制成固相 抗 体,往包被 单抗 的微孔中依次
人白细胞介素-17A(IL-17A)酶联免疫分析(ELISA)
人 白细胞介素-17A(IL-17A) 酶联免疫 分析( ELISA ) 试剂 盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中白细胞介素-17A(IL-17A)含量。 实验原理 : 本试剂盒应用双抗体夹心法测定 标本 中 人白细胞介素-17A ( IL-17A ) 水平。用纯化的 人白细胞介素-17A ( IL-17A ) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次
Immunity:「填补教科书」董晨院士团队解析 IL-17D 重要功能,并首次发现其受体
慢性炎症与自身免疫性疾病、过敏性疾病和肿瘤的发展密切相关,炎性因子白介素 - 17(IL-17)家族在促进宿主防御和自身免疫性疾病中起着重要作用。IL-17 家族由六个成员组成(包括 IL-17A、B、C、D、E、F),IL-17D 是 IL-17 家族中了解最少的成员,其受体也尚不明确。 图片来源:Frontiers in Immunology(1)2021 年 4 月 13 日,清华大学医学院董晨院士团队在 Immunity 上在线发表了题为 Interleukin-17
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