Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
形态:
-
亚型:
-
免疫原:
-
规格:
100ul/50ul
规格:
100ul
产品价格:
¥2300.0
规格:
50ul
产品价格:
¥1500.0
别名
IL-17抗体;Interleukin-17, CTLA 8, CTLA8, Cytotoxic T lymphocyte associated antigen 8, Cytotoxic T lymphocyte associated protein 8, Cytotoxic T lymphocyte associated serine esterase 8, IL 17A, IL17A, IL-17A, Interleukin 17, Interleukin 17A, Interleukin17, Interleukin17A. , ,
宿主
Rabbit
特异性
IL-17
反应种属
Mouse;Rat;
应用
WB=1:500-2000
分子量
Predicted molecular weight: 15kDa Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
免疫原
KLH conjugated synthetic peptide derived from mouse IL-17 (85-150aa):85-150/150
浓度
1mg/ml
纯化方法
affinity purified by Protein A
类型
Polyclonal Antibody
同种型
IgG
储存/保存方法
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
存储溶液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
研究领域
肿瘤 细胞生物 免疫学 转录调节因子
背景说明
IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17.