PCL 016,98-98-6

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抑制剂描述：

产品名称：PCL 016

产品别名：见爱必信官网

英文别名：PCL 016

靶点：Human Endogenous Metabolite

CAS：98-98-6

纯度：＞98%

外观：见爱必信官网

保存方法：Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

描述：PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.

溶解性：DMSO : ≥ 100 mg/mL (812.28 mM)
H2O : ≥ 50 mg/mL (406.14 mM)

体外研究：

体内研究：Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations.

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