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- 爱必信(absin)
- 上海
- abs822112
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
- 库存：
99
- 供应商：
爱必信(上海)生物科技有限公司
- CAS号：
415697-08-4
- 规格：
25mg/5mg
| 规格： | 25mg | 产品价格： | ￥7050.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥2350.0 |
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抑制剂描述： 产品名称：SN 6 产品别名：见爱必信官网 英文别名：SN 6 靶点：Na+/Ca2+ Exchanger CAS：415697-08-4 纯度：98% 外观：见爱必信官网 保存方法：Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. 描述：SN 6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor, and inhibits 45Ca2+ uptake by NCX1, NCX2, and NCX3, with IC50s of 2.9, 16, and 8.6 μM, respectively. 溶解性：DMSO : 62.5 mg/mL (155.29 mM; Need ultrasonic) 体外研究： SN 6 is a selective Na+/Ca2+ exchanger inhibitor, which inhibits the initial rate of 45Ca2+ uptake into NCX1, NCX2, and NCX3 transfectants with IC50 values of 2.9 ± 0.12, 16 ± 1.1, and 8.6 ± 0.27 μM. SN 6 (up to 30 μM) also less potently inhibits muscarinic acetylcholine receptor, with a higher IC50 of 18 μM. SN 6 (0.3-30 μM) completely inhibits the initial rate of Na+i-dependent 45Ca2+ uptake into Na+-loaded sarcolemmal vesicles in a dose dependent manner (IC50, 5.3 ± 0.37 μM). SN 6 (0.3-10 μM) dose-dependently protects against the hypoxia/reoxygenation-induced LDH release in parental LLC-PK1 cells and NCX1 transfectants but not in K229Q transfectants. SN 6 (1-30 μM) suppresses the bidirectional outward and inward INCX in a concentration-dependent manner, with IC50 values of 2.3 μM and 1.9 μM, respectively. SN 6 also inhibits bidirectional current (INCX) in a [Na+]i concentration-dependent manner, with IC50 values of 3.4 μM, 2.3 μM, and 1.1 μM at 10 mM, 20 mM, and 30 mM [Na+]i, respectively. SN 6 inhibits hypoxia/reoxygenation-induced LDH release with an IC50 value of 0.63 ± 0.15 μM in NCX1 transfectants. 体内研究：
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文献和实验【共享】08新书：Protein Engineering (Nucleic Acids and Molecular Biology).pdf
08新书：Protein Engineering (Nucleic Acids and Molecular Biology).pdf by Caroline Koehrer, Uttam L. RajBhandary Springer | 2008-10-21 | ISBN: 3540709371 | 347 pages | PDF | 7,5 MB Site-specific mutagenesis of DNA, developed some thirty years ago
PCR Protocol(per Adam 08/12/04) 【University of Chicago】
The Preuss Lab,The Division of Biological Sciences,The University of Chicago PCR.html">http://preuss.bsd.uchicago.edu/protocols/PCR.html 上一篇：TAIL PCR Protocol 下一篇：RT-PCR Protocol
Shorty DNA Prep (per Adam 08/12/04)【University of Chicago】
There are several ways to prepare DNA
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