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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
- 库存:
99
- 供应商:
爱必信(上海)生物科技有限公司
- CAS号:
1695533-89-1
- 规格:
25mg/5mg
| 规格: | 25mg | 产品价格: | ¥9526.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥3440.0 |
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抑制剂描述: 产品名称:KO-947 产品别名:见爱必信官网 英文别名:KO-947 靶点:ERK CAS:1695533-89-1 纯度: 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述:KO-947 is a potent and selective inhibitor of ERK1/2 kinases with potential clinical utility in MAPK pathway dysregulated tumors. 溶解性: 体外研究: KO-947 is a 10 nM inhibitor of ERK with at least 50-fold selectivity against a panel of 450 kinases. KO-947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling, including mutations in BRAF, NRAS or KRAS, at low nanomolar concentrations. 体内研究:KO-947 is a 10 nM inhibitor of ERK with at least 50-fold selectivity against a panel of 450 kinases. KO-947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling, including mutations in BRAF, NRAS or KRAS, at low nanomolar concentrations.
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文献和实验网络 幽门螺杆菌感染947例临床分析 我院自1994-11~1996-04共对1448名患者进行纤维胃镜检查并做幽门螺杆菌(Hp)检查,其中Hp阳性947例。现报告如下。 1 对象和方法 1.1 对象 本组Hp阳性947例,男566例,女381例,男女之比1.49.1。年龄11岁~81岁。20岁95例(10.0%);男39例,女
身高组段(1) 频数(2) 累计频数*(3) 累计频率(%)(4) 概率单位(5) 162~ 1 1 0.9 2.63 164~ 4 5 4.5 3.30 166~ 9 14 12.7 3.86 168~ 13 27 24.5 4.31 170~ 19 46 41.8 4.79 172~ 27 73 66.4 5.42 174~ 16 89 80.9 5.87 176~ 8 97 88.2 6.19 178~ 8 105 95.5 6.70 180~ 3 108 98.2
Design and Generation of Gene‐Targeting Vectors
are followed by protocols for the construction of vectors to generate knockout (KO), conditional KO, and subtle mutant alleles. Curr. Protoc. Mouse Biol. 1:199?211. © 2011 by John Wiley & Sons, Inc. Keywords: gene targeting; conditional KO
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