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- 技术资料
- 抗体名：
TSG101抗体
- 抗体英文名：
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- 靶点：
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- 浓度：
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- 应用范围：
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- 宿主：
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- 适应物种：
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- 保质期：
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- 抗原来源：
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- 目录编号：
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- 级别：
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- 库存：
现货
- 供应商：
爱必信(上海)生物科技有限公司
- 标记物：
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- 克隆性：
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- 保存条件：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
- 形态：
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- 亚型：
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- 免疫原：
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- 规格：
50ug/100ug
| 规格： | 50ug | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥2300.0 |
| 别名 | TSG101抗体;ESCRT I complex subunit TSG101, ESCRT-I complex subunit TSG101, TS101_HUMAN, TSG 10, TSG 101, TSG10, Tsg101, Tumor susceptibility gene 10, Tumor susceptibility gene 101, Tumor susceptibility gene 101 protein, Tumor susceptibility protein, Tumor susceptibility protein isoform 3, VPS 23, VPS23, |
| 宿主 | Rabbit |
| 特异性 | TSG101 Antibody detects endogenous levels of total TSG101. |
| 反应种属 | Human;Mouse;Monkey |
| 预测反应种属 | Rabbit;Dog;Horse |
| 应用 | WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000 |
| 分子量 | Predicted molecular weight: 44kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 | A synthesized peptide derived from Human TSG101(Accession Q99816), corresponding to amino acid residues S172-P197. |
| 浓度 | 1mg/ml |
| 纯化方法 | The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin . |
| 类型 | Polyclonal Antibody |
| 储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| 存储溶液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
| 背景说明 | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). |
| 组织特异性 | Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas. |
| 翻译后修饰 | Monoubiquitinated at multiple sites by LRSAM1 and by MGRN1. Ubiquitination inactivates it, possibly by regulating its shuttling between an active membrane-bound protein and an inactive soluble form. Ubiquitination by MGRN1 requires the presence of UBE2D1. |
| 细胞定位 | Cytoskeleton;Cytosol;Endosome;Extracellular region or secreted;Nucleus;Plasma Membrane; |
| UniProt | Q99816 |
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文献和实验该产品被引用文献
- MALDI-TOF Mass Spectrometry Profiling of Plasma Exosomes Evaluates Osteosarcoma MetastasisZhenzhen Han, Cheng Peng, Jia Yi, Yiwen Wang, Qi Liu, Yi Yang, Shuping Long, Liang Qiao, Yuhui Shen
Iscience. 2021 Aug 20 ; 8
影响因子： 5.08
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Rabbit anti-TSG101 Polyclonal Antibody,TSG101抗体
￥1500 - 2300
