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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
DMPAC-Chol
- 库存:
10
- 供应商:
TargetMol
- CAS号:
184582-91-0
- 规格:
5 mg/10 mg/1 mg
| 规格: | 5 mg | 产品价格: | ¥1900.0 |
|---|---|---|---|
| 规格: | 10 mg | 产品价格: | ¥3220.0 |
| 规格: | 1 mg | 产品价格: | ¥560.0 |
Product Introduction
Bioactivity
英文名:DMPAC-Chol
描述:DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 μg/ml.

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文献和实验towards degradation by exo- and endonucleases in serum and in tissue homogenates. The conjugation of cholesterol to the 3' end of the sense strand of a siRNA molecule by means of a pyrrolidine linker (thereby generating chol-siRNA) did not result in a significant loss
Lipoplex Formation Using Liposomes Prepared by Ethanol Injection
Cationic liposomes composed of 3β-[N -(N� N� –dimethylaminoethane)carbamoyl] cholesterol (DC–Chol) and dioleoylphosphatidylethanolamine (DOPE) (DC–Chol/DOPE liposome, molar ratio, 1:1 or 3:2) prepared by the dry-film method
LPD Nanoparticles-Novel Nonviral Vector for Efficient Gene Delivery
. One is composed of cationic lipid d io leoyl-t rimethyla mmonium p ropane (DOTAP) and cholesterol at molar ratio of 1:1. The other is composed of cationic lipid 3β(N-(N’, N’-d imethylaminoethane) c arbamoyl) chol esterol (DC-Chol) and neutral lipid d io leoylp
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