Beclometasone dipropionate mon

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Beclometasone dipropionate monohydrate

CAS No. : 77011-63-3

MCE 国际站：Beclometasone dipropionate monohydrate

产品活性：Beclometasone dipropionate monohydrate 是 Beclometasone 的前体活性分子，是口服有效的糖皮质激素受体激动剂。Beclometasone dipropionate monohydrate 通过糖皮质激素受体发挥作用，抑制炎症和过度增殖。Beclometasone dipropionate monohydrate 可用于哮喘研究。

研究领域：Immunology/Inflammation  |  Vitamin D Related/Nuclear Receptor  |  Metabolic Enzyme/Protease  |  NF-κB

作用靶点：Glucocorticoid Receptor  |  Reactive Oxygen Species  |  NO Synthase

In Vitro: Beclometasone dipropionate monohydrate (1-100 nM; 20 min) inhibits STAT-1 expression and reduces the levels of iNOS, ROS and NT generated by rhIL-17A in 16HBE cells.

In Vivo: Beclometasone dipropionate monohydrate (150 µg/kg; nebulization; male BALB/c mice) relieves asthma and decreases total cell number and relative eosinophil number.

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