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MedChemExpress LLC
- CAS号:
2566497-96-7
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询盘
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Antitumor agent-68
CAS No. : 2566497-96-7
MCE 国际站:Antitumor agent-68
产品活性:Antitumor agent-68 是一种有效的微管蛋白抑制剂。Antitumor agent-68 具有较好的抗癌活性,其对 HeLa 和 MCF-7 的 IC50 值分别为 3.6 和 3.8 μM。Antitumor agent-68 能以剂量依赖的方式减少 ROS 的产生和清除 DPPH 自由基。
研究领域:Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease | Cytoskeleton | Cell Cycle/DNA Damage
作用靶点:Reactive Oxygen Species | Microtubule/Tubulin
In Vitro: Antitumor agent-68 (Compound 7) exhibits anticancer activity with IC50s of 3.6 and 3.8 μM, for HeLa and MCF-7 cells, respectively.
Antitumor agent-68 (10 μΜ; 24 hours) causes a 3-fold reduction of ROS production induced by Men in 3T3-L1 cells, and an EC50 of DPPH radical scavenging is 8.30 µg/mL.
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