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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
ACLY
- 应用范围:
WB 1:2000, IHC 1:50, IF 1:100
- 宿主:
Mouse
- 适应物种:
Human, Mouse, Rat
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 标记物:
Unconjugated
- 克隆性:
Monoclonal Antibody
- 保存条件:
Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态:
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
- 亚型:
IgG1
- 免疫原:
Full length human recombinant protein of human ACLY (NP_001087) produced in HEK293T cell.
- 规格:
100 ug
产品概述:Carrier-free (BSA/glycerol-free) ACLY mouse monoclonal antibody, clone LBI3G8
总结:ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
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文献和实验secondary antibody review -- data from 99 publications
Signaling 18 IgG Alexa Fluor 488 immunocytochemistry 1:2000 18 IgG Alexa Fluor 568 immunocytochemistry 1:2000 19 donkey IgG HRP western blot 1:3000 detect antibody binding in mouse epithelial cells Amersham Biosciences 19 goat
Detection of apoptotic process in situ using immunocytochemical and TUNEL assays
from invertebrates to lower and higher verterbrates, and intervenes both in physiological and in pathological states, such as normal cell turnover, embryogenesis, metamorphosis, thymic maturation and involution, neoplasm, etc. (1-4). A mouse anti-DNA monoclonal
population is termed monoclonal . It recognizes a single epitope on the antigenic protein. Antibody producing B lymphocytes can be isolated from the spleen or from lymph nodes. However, they have a finite life span in culture, i.e
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